Why Onset

After an unbuffered injection, the body must raise the pH of the anesthetic towards physiologic pH (7.4) before the patient can achieve pulpal anesthesia.

Buffering raises the pH of local anesthetic closer to physiological, making your local anesthetic of choice better and more predictable. Onset lets you buffer cartridges of local anesthetic at chairside immediately before delivering the injection, making buffering simple, convenient and predictable.  

 

Making your local anesthetic better and more predictable

• Local anesthetics are manufactured at a low (acidic) pH when they arrive at your practice. After injection, the body must raise the pH of the anesthetic towards physiologic (7.4) before the patient can achieve pulpal anesthesia. This process keeps you, your staff and your patient waiting while the body works to raise the pH towards physiologic.
• Onset instantly buffers the local anesthetic in the cartridge immediately before it is loaded into the syringe to administer the injection.  Buffering the local anesthetic outside the body before the injection takes time and the patient’s physiology out of the buffering process. This makes your local anesthetic better and more predictable.
• Using Onset, your local anesthetic injection can have the pH of normal saline, instead of lemon juice!
• The Onset Buffering System allows you to buffer 4 of the 5 major local anesthetics used in dentistry: articaine, lidocaine, prilocaine and mepivacaine.
• At Onpharma, we understand you want to use YOUR local anesthetic, YOUR syringe and YOUR technique. With Onset, you can!